New scanner aims to spot blood vessel inflammation more clearly

NCT ID NCT07628075

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study will test a new type of PET/CT scanner, called Long-Axial Field-of-View (LAFOV), to see if it can better detect inflammation in the walls of large arteries in people with large vessel vasculitis (LVV). The scanner is more sensitive and can image the whole body faster, potentially allowing for lower radiation doses and clearer pictures. Researchers will compare scans from 18 participants (12 with LVV and 6 healthy volunteers) to develop a standardized imaging protocol for future use.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Imperial College Healthcare NHS Trust

    London, Greater London, W2 1NY, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • King's College London

    London, Greater London, SE1 7EH, United Kingdom

    Contact

    Contact Email: •••••@•••••

  • Royal Free London NHS Foundation Trust

    London, Greater London, NW3 2QG, United Kingdom

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

[18F]FDG (a radioactive sugar) and CT contrast dye

What this could lead to

If successful, this could lead to a standardized, more accurate imaging protocol for diagnosing and monitoring large vessel vasculitis, potentially reducing unnecessary treatments.

What could go wrong

This is a small, early-phase study (18 participants) focused on optimizing the imaging technique, not testing a treatment. The new method may not prove significantly better than current scans.

Conditions

The condition(s) this trial relates to.

Giant Cell Arteritis Takayasu arteritis temporal arteritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.