Massive west african trial takes on deadly lassa fever with new drug cocktail
NCT ID NCT06212336
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This large clinical trial in West Africa is testing several drugs—including favipiravir, ribavirin, dexamethasone, and a new drug called ARN-75039—to find a better treatment for Lassa fever, a viral disease that kills thousands each year. The study will enroll about 1,755 hospitalized patients and measure whether these drugs reduce death and organ failure compared to standard care. The goal is to find a safer and more effective option than the current treatment, ribavirin, which has serious side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Favipiravir, Ribavirin, Dexamethasone, ARN-75039
What this could lead to
If successful, this trial could identify a safer and more effective treatment for Lassa fever, potentially saving thousands of lives in West Africa.
What could go wrong
This is an early-to-mid stage trial, and the drugs may not prove more effective than current care. Ribavirin has known toxicity, and new drugs like ARN-75039 are still being tested for safety.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Abubakar Tafawa Balewa University Teaching Hospital
NOT_YET_RECRUITINGBauchi, Nigeria
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Federal Medical Center Owo
RECRUITINGOwo, Ondo State, Nigeria
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Irrua Specialist Teaching Hospital
RECRUITINGIrrua, Edo, Nigeria
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Phebe Hospital
NOT_YET_RECRUITINGSuacoco, Bong County, Liberia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact