New oral drug shows promise against deadly lassa fever in west africa trial

NCT ID NCT07419373

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study tests a new oral antiviral drug, ARN-75039, for treating Lassa fever, a serious viral illness common in West Africa. About 135 hospitalized adults will receive either a high or low dose of the new drug or the standard IV treatment, ribavirin, for 10 days. The goal is to see if the new pill is safe and can reduce the virus faster than the current treatment.

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Conditions

The condition(s) this trial relates to.

Communicable Diseases, Emerging Lassa fever Neglected Diseases viral hemorrhagic fever

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Abubakar Tafawa Balewa University Teaching Hospital

    Bauchi, Nigeria

  • Arisan Therapeutics

    Carlsbad, California, 92008, United States

  • Federal Medical Centre, Owo

    Owo, Ondo State, Nigeria

  • Irrua Specialist Teaching Hospital

    Irrua, 310115, Nigeria

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