New hope for breast cancer survivors: laser treatment may ease vaginal pain without hormones

This study tests whether a CO2 laser combined with a regenerative cream can safely relieve vaginal atrophy symptoms—like dryness, pain during sex, and burning—in 180 breast cancer survivors who cannot use hormone therapy. Participants will receive the laser treatment plus cream, and researchers will measure symptom changes, vaginal health, and quality of life. The goal is to find a non-hormonal option for a common and distressing side effect of breast cancer treatment.