New laser approach aims to stop melasma relapses
NCT ID NCT06644157
First seen Jan 02, 2026
Summary
This study tests whether a special 1064nm laser can treat melasma and prevent it from returning. Thirty adults with moderate to severe melasma will use a depigmenting cream and sunscreen on their whole face, while one side of the face also gets laser sessions every other week for 12 weeks. Researchers will compare the laser-treated side to the untreated side to see if the laser improves results and reduces relapses.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU de Nice - Hôpital de l'Archet
Nice, Alpes-Maritimes, 06200, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
1064nm 650 microsecond laser (Aerolase Neo Elite device)
What this could lead to
If successful, this laser treatment could reduce melasma severity and help prevent relapses when combined with standard depigmenting cream and sunscreen.
What could go wrong
This is a small early-stage study with only 30 participants, so results may not apply to everyone. The laser may cause temporary redness or discomfort, and melasma often returns without ongoing care.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.