World-First larynx transplant trial offers new hope for silent patients
NCT ID NCT02821299
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study will test laryngeal transplantation in 3 adults who have permanently lost the ability to speak, breathe, or swallow normally due to severe larynx damage. The goal is to restore these functions using a donor larynx, with a new nerve reconnection technique to improve outcomes. Patients will need lifelong immunosuppressive drugs to prevent rejection, so the procedure is reserved for those with no other treatment options.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre de soins de suite et de réadaptation fonctionnelle - SSR Val Rosay
RECRUITINGSaint-Didier-au-Mont-d'Or, 69370, France
Contact
Contact
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Service ORL & Chirurgie Cervicofaciale - Hôpital Charles Nicolle - CHU Rouen
RECRUITINGRouen, 76000, France
Contact
Contact
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Service d'Urologie et Chirurgie de la Transplantation - Hôpital Edouard Herriot - Hospices Civils de Lyon
RECRUITINGLyon, 69003, France
Contact
Contact
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