World-First larynx transplant trial aims to give voice back to three patients
NCT ID NCT02821299
First seen Feb 21, 2026 · Last updated Apr 24, 2026 · Updated 9 times
Summary
This study tests laryngeal (voice box) transplantation in 3 adults who have permanently lost the ability to speak, breathe, and swallow normally due to severe injury. The goal is to restore these functions using a donor larynx, with a new nerve reconnection technique to improve outcomes. Participants will need to take lifelong immunosuppressive drugs to prevent rejection, so this is a disease-control approach, not a cure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre de soins de suite et de réadaptation fonctionnelle - SSR Val Rosay
RECRUITINGSaint-Didier-au-Mont-d'Or, 69370, France
Contact
Contact
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Service ORL & Chirurgie Cervicofaciale - Hôpital Charles Nicolle - CHU Rouen
RECRUITINGRouen, 76000, France
Contact
Contact
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Service d'Urologie et Chirurgie de la Transplantation - Hôpital Edouard Herriot - Hospices Civils de Lyon
RECRUITINGLyon, 69003, France
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Conditions
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