Breakthrough drug trial aims to save lives from deadly alcohol hepatitis

NCT ID NCT07428538

Summary

This study is testing whether an experimental drug called larsucosterol can help people with severe alcohol-associated hepatitis survive longer without needing a liver transplant. Researchers will enroll 350 adults who are hospitalized with this serious liver condition. The main goal is to see if the drug improves survival rates at 90 days compared to standard care.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AdventHealth Transplant Institute

    NOT_YET_RECRUITING

    Orlando, Florida, 32804, United States

  • Banner - University Medical Center, Phoenix, Arizona

    NOT_YET_RECRUITING

    Phoenix, Arizona, 85006, United States

  • Baylor College of Medicine (BCM) - Baylor Clinic

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

  • Baylor Scott White Research Institute - Dallas

    NOT_YET_RECRUITING

    Dallas, Texas, 75246, United States

  • Beth Israel Deaconess Medical Center

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02215, United States

  • Bon Secours Liver Institute of Richmond

    NOT_YET_RECRUITING

    Richmond, Virginia, 23226, United States

  • Boston University School of Medicine

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02118, United States

  • Cedars Sinai Medical Center

    NOT_YET_RECRUITING

    Los Angeles, California, 90048, United States

  • Georgetown University Medical Center

    NOT_YET_RECRUITING

    Washington D.C., District of Columbia, 20007, United States

  • Henry Ford Hospital System

    NOT_YET_RECRUITING

    Detroit, Michigan, 48202, United States

  • Intermountain Transplant Clinic

    NOT_YET_RECRUITING

    Murray, Utah, 84107, United States

  • Johns Hopkins Hospital

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21287, United States

  • Levine Cancer Institute / Atrium Health

    NOT_YET_RECRUITING

    Charlotte, North Carolina, 28204, United States

  • Marshall Health

    NOT_YET_RECRUITING

    Huntington, West Virginia, 25701, United States

  • Massachusetts General Hospital

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic - Phoenix

    NOT_YET_RECRUITING

    Phoenix, Arizona, 85054, United States

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

  • Mercy Medical Center - The Institute for Digestive Health and Liver Disease

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21202, United States

  • NYU Langone Health

    NOT_YET_RECRUITING

    New York, New York, 10016, United States

  • Northwell Health Physician Partners Sandra Atlas Bass Center for Liver Diseases

    NOT_YET_RECRUITING

    Manhasset, New York, 11030, United States

  • Penn State Health, Milton S. Hershey Medical Center

    NOT_YET_RECRUITING

    Hershey, Pennsylvania, 17033, United States

  • Piedmont Atlanta Hospital - Piedmont Transplant Institute

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30309, United States

  • Richmond VA Medical Center

    NOT_YET_RECRUITING

    Richmond, Virginia, 23249, United States

  • Robley Rex VA Medical Center

    NOT_YET_RECRUITING

    Louisville, Kentucky, 40206, United States

  • Rush University Medical Center

    NOT_YET_RECRUITING

    Chicago, Illinois, 60612, United States

  • Rutgers University New Jersey Medical School

    NOT_YET_RECRUITING

    Newark, New Jersey, 07103-2425, United States

  • Southern California GI & Liver Centers - Coronado

    NOT_YET_RECRUITING

    Coronado, California, 92118, United States

  • Stanford Medicine - Clinical and Translational Research Unit - Redwood City

    NOT_YET_RECRUITING

    Redwood City, California, 94063, United States

  • Sutter Health

    NOT_YET_RECRUITING

    San Francisco, California, 94109, United States

  • Tampa General Hospital

    NOT_YET_RECRUITING

    Tampa, Florida, 33606, United States

  • Temple University Hospital

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19140, United States

  • The Liver Institute at Methodist Dallas Medical Center

    RECRUITING

    Dallas, Texas, 75203, United States

  • The Ohio State University Wexner Medical Center (OSUWMC)

    NOT_YET_RECRUITING

    Columbus, Ohio, 43210, United States

  • Thomas Jefferson University Hospital

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • Tulane University Health Sciences Center - Tulane Avenue

    NOT_YET_RECRUITING

    New Orleans, Louisiana, 70112, United States

  • UCLA Health - Ronald Reagan Medical Center

    NOT_YET_RECRUITING

    Los Angeles, California, 90095, United States

  • UMass Chan Medical School

    NOT_YET_RECRUITING

    Worcester, Massachusetts, 01655, United States

  • University Hospitals Cleveland Medical Center

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44106, United States

  • University of Alabama at Birmingham (UAB) Hospital

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35294, United States

  • University of California at Davis Medical Center

    NOT_YET_RECRUITING

    Sacramento, California, 95757, United States

  • University of Iowa Hospitals & Clinics

    NOT_YET_RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Michigan

    NOT_YET_RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of Minnesota Medical Center

    NOT_YET_RECRUITING

    Minneapolis, Minnesota, 55414-2924, United States

  • University of New Mexico (UNM) Hospital

    NOT_YET_RECRUITING

    Albuquerque, New Mexico, 87106-4713, United States

  • University of Pennsylvania Hospital

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • University of Utah Health - University of Utah

    NOT_YET_RECRUITING

    Salt Lake City, Utah, 84132, United States

  • University of Virginia Health

    NOT_YET_RECRUITING

    Charlottesville, Virginia, 22908, United States

  • VA Medical Center - Philadelphia

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19104-4551, United States

Conditions

Explore the condition pages connected to this study.