Tracking a precision cancer drug in real patients

NCT ID NCT04142437

Recruiting now Disease control Sponsor: Bayer Source: ClinicalTrials.gov ↗

Summary

This study aims to learn more about how well the approved drug larotrectinib (VITRAKVI) works and how safe it is during routine use for patients with advanced solid tumors caused by a specific genetic change called an NTRK gene fusion. Researchers will observe about 150 adults and children for up to 5 years, collecting information from their normal medical care. The goal is to understand the drug's real-world benefits and side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Allegheny Health Network
TERMINATED

Pittsburgh, Pennsylvania, 15212, United States
Atlantic Hem Onc / Morristown Medical Center
WITHDRAWN

Morristown, New Jersey, 07960, United States
Banner Desert Medical Center
WITHDRAWN

Mesa, Arizona, 85202, United States
Boston Children's / Dana Farber
WITHDRAWN

Boston, Massachusetts, 02215, United States
California Research Inst.
RECRUITING

Los Angeles, California, 90027, United States
Cancer Center of Kansas
RECRUITING

Wichita, Kansas, 67214, United States
Children's Hospital of Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Detroit Clinical Research Center
RECRUITING

Farmington Hills, Michigan, 48334, United States
East Carolina University / Vidant Health
RECRUITING

Greenville, North Carolina, 27834, United States
Fort Wayne Medical Oncology Hematology
RECRUITING

Fort Wayne, Indiana, 46804, United States
Frederick Health-James M Stockman Cancer Institute
TERMINATED

Frederick, Maryland, 21702, United States
Great Lakes Cancer Center
TERMINATED

Buffalo, New York, 14210, United States
Gundersen Health System
RECRUITING

La Crosse, Wisconsin, 54601, United States
Hoag Memorial Hospital Presbyterian
RECRUITING

Newport Beach, California, 82663, United States
Intermountain Healthcare - Dixie Regional Medical Center
WITHDRAWN

St. George, Utah, 84790, United States
Intermountain Healthcare - Intermountain Medical Center
WITHDRAWN

Murray, Utah, 84107, United States
Johns Hopkins / Sidney Kimmel Cancer Center
RECRUITING

Baltimore, Maryland, 21205, United States
Levine Cancer Center
WITHDRAWN

Charlotte, North Carolina, 28204, United States
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
WITHDRAWN

Torrance, California, 90502, United States
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Maine Health
RECRUITING

South Portland, Maine, 04106, United States
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, Argentina
Many Locations
NOT_YET_RECRUITING

Multiple Locations, Australia
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, Austria
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, Belgium
Many Locations
WITHDRAWN

Multiple Locations, Brazil
Many Locations
COMPLETED

Multiple Locations, Canada
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, China
Many Locations
WITHDRAWN

Multiple Locations, Denmark
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, Finland
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, France
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, Germany
Many Locations
NOT_YET_RECRUITING

Multiple Locations, Greece
Many Locations
WITHDRAWN

Multiple Locations, Ireland
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, Italy
Many Locations
WITHDRAWN

Multiple Locations, Japan
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, Luxembourg
Many Locations
WITHDRAWN

Multiple Locations, Norway
Many Locations
WITHDRAWN

Multiple Locations, Russia
Many Locations
WITHDRAWN

Multiple Locations, Singapore
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, South Korea
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, Spain
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, Sweden
Many Locations
ACTIVE_NOT_RECRUITING

Multiple Locations, Switzerland
Many Locations
WITHDRAWN

Multiple Locations, Taiwan
Many Locations
NOT_YET_RECRUITING

Multiple Locations, United Kingdom
Mayo Clinic
WITHDRAWN

Jacksonville, Florida, 32224, United States
Medical Univ. of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Memorial Sloan Kettering Children's Cancer Center
RECRUITING

New York, New York, 10065, United States
Mercy Health Youngstown
RECRUITING

Youngstown, Ohio, 44501, United States
Nemours Children's Hospital
WITHDRAWN

Orlando, Florida, 32827, United States
Nevada Cancer Research Foundation
RECRUITING

Las Vegas, Nevada, 89169, United States
Nicklaus Children's Hospital
RECRUITING

Miami, Florida, 33155, United States
Ohio State Comp. Cancer Ctr. / James Cancer Hospital
WITHDRAWN

Columbus, Ohio, 43210, United States
Providence Health System - Southern California
TERMINATED

Santa Monica, California, 90404, United States
Regional Health Hope Center
WITHDRAWN

Terre Haute, Indiana, 47802, United States
Rutgers Cancer Institute of New Jersey
WITHDRAWN

New Brunswick, New Jersey, 08901, United States
SCL Health
WITHDRAWN

Grand Junction, Colorado, 81501, United States
SSM Health Cancer Center - Dean Medical Group
TERMINATED

Madison, Wisconsin, 53717, United States
Seattle Children's
RECRUITING

Seattle, Washington, 98105, United States
Sparrow Cancer Center
RECRUITING

Lansing, Michigan, 48912, United States
St. Jude Children's Research Hospital
WITHDRAWN

Memphis, Tennessee, 38105, United States
Stanford Univ Med Ctr. / Lucile Packard Children's Hosp
RECRUITING

Palo Alto, California, 94304, United States
Staten Island Univ. Hospital (Northwell Health)
WITHDRAWN

Staten Island, New York, 10305, United States
Tufts / Neely Cancer Center
RECRUITING

Boston, Massachusetts, 02111, United States
UCLA - Mattel Children's Hospital
RECRUITING

Los Angeles, California, 90095, United States
UCSF Benioff Children's Hospital Oakland
WITHDRAWN

Oakland, California, 94609, United States
USC / Norris Comprehensive Cancer Center
WITHDRAWN

Los Angeles, California, 90089, United States
UT Southwestern Medical Center / Children's Health
RECRUITING

Dallas, Texas, 75390, United States
Univ. of Maryland / Greenebaum Comp. Cancer Ctr.
WITHDRAWN

Baltimore, Maryland, 21201, United States
Univ. of Utah / Huntsman Cancer Center
RECRUITING

Salt Lake City, Utah, 84112, United States
University of Miami
RECRUITING

Miami, Florida, 33146, United States
University of Pennsylvania (Penn Med)
WITHDRAWN

Philadelphia, Pennsylvania, 19104, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States
West Virginia University
RECRUITING

Morgantown, West Virginia, 26506, United States
Yale University
RECRUITING

New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.

LOCALLY ADVANCED OR METASTATIC SOLID TUMOR HARBORING AN NTRK GENE FUSION