Knot or clip? study tests best way to seal the appendix after removal

NCT ID NCT07281612

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed trial looked at 190 people having laparoscopic appendix removal. It compared closing the appendix stump with a hand-tied knot versus a plastic clip. The goal was to see which method leads to fewer problems like infection or slow bowel recovery within 15 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If one method proves better, it could guide surgeons on the safest way to close the appendix stump, reducing complications after surgery.
What could go wrong
This is a small, early-phase trial (190 people) comparing two common techniques, so results may not be definitive or apply to all patients. Neither method is new or groundbreaking.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AIMS

    Muzaffarabad, AJK/Punjab, 60000, Pakistan

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