Knot or clip? study tests best way to seal the appendix after removal
NCT ID NCT07281612
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed trial looked at 190 people having laparoscopic appendix removal. It compared closing the appendix stump with a hand-tied knot versus a plastic clip. The goal was to see which method leads to fewer problems like infection or slow bowel recovery within 15 days after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If one method proves better, it could guide surgeons on the safest way to close the appendix stump, reducing complications after surgery.
What could go wrong
This is a small, early-phase trial (190 people) comparing two common techniques, so results may not be definitive or apply to all patients. Neither method is new or groundbreaking.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AIMS
Muzaffarabad, AJK/Punjab, 60000, Pakistan