New drug may stop common heart rhythm problem after surgery

NCT ID NCT04607122

First seen Apr 13, 2026 · Last updated May 15, 2026 · Updated 4 times

Summary

This study tested whether a low-dose drug called landiolol can prevent atrial fibrillation (a type of irregular heartbeat) in 400 non-Asian adults after heart surgery. Atrial fibrillation is common after such operations and can lead to complications. The drug was given as a continuous infusion in the ICU and compared to a placebo. The goal was to see if landiolol reduces the chance of developing this heart rhythm problem without causing dangerous low blood pressure or slow heart rate.

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Contacts and locations

Locations

  • CMC Ambroise Paré

    Neuilly-sur-Seine, 92200, France

  • Centre Cardiologique du Nord

    Saint-Denis, 93200, France

  • Hôpital Privé Jacques Cartier

    Massy, 91300, France

Conditions

Explore the condition pages connected to this study.