Could a milk protein help ICU patients survive?

NCT ID NCT05936528

Completed Disease control Sponsor: Mansoura University Hospital Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This trial investigates whether lactoferrin, a protein found in milk with anti-inflammatory and antimicrobial properties, can improve survival and reduce complications in critically ill adults in the intensive care unit. About 660 ICU patients will receive either lactoferrin plus standard care or standard care alone. The study measures 28-day death rates, need for breathing machines, and length of ICU stay.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Lactoferrin
What this could lead to: If it works, lactoferrin could become a simple, safe addition to standard ICU care to reduce deaths and shorten hospital stays.
What could go wrong: This is a single-blind trial, and results may not apply to all ICU patients. Lactoferrin may show no benefit over standard therapy, and allergic reactions are possible.

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Conditions

The condition(s) this trial relates to.

Critical Illness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL ILLNESS

Contacts and locations

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Locations

Mansoura University hospital

Al Mansurah, El-dakhlia, 35511, Egypt

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