Could unmet pain relief hopes raise postpartum depression risk?
NCT ID NCT07292649
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether having your expectations for labor pain relief met or not affects your chance of developing postpartum depression. Researchers will follow 3640 women planning a vaginal delivery and compare depression rates six months after birth between those whose pain relief expectations were met and those whose were not. The goal is to better understand the link between labor pain management and mental health after childbirth.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 3,640 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Jun 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of patients undergoing a spontaneous or induced vaginal delivery, regardless of whether they request epidural analgesia.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Signed informed consent * Planned vaginal delivery (spontaneous or induced) * Pregnancy * Age \> 18 years Exclusion Criteria: * Allergy to local anesthetics * Language barrier * Contraindications to labor analgesia * Delivery by Cesarean section * Known history of psychiatric disorders (including major depression)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Hospital of Padova
RECRUITINGPadova, Veneto, 35127, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could more doula visits ease postpartum depression?
- A healing hand: could Doula-Midwife teams transform postpartum recovery for NICU moms?
- Magnetic pulses to the brain: a Drug-Free hope for peripartum depression?
- Can a wearable light device lift the fog of postpartum depression?
- Can believing in brain stimulation make it work better?
- Seeing the needle: ultrasound may take the guesswork out of labor pain relief