Can a traditional chinese herb tame stubborn rheumatoid arthritis?
NCT ID NCT07721142
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This trial investigates whether adding Kunxian Capsule, a traditional Chinese herbal remedy, to standard medications (methotrexate and tofacitinib) can improve outcomes for people with refractory rheumatoid arthritis — a form that does not respond well to usual treatments. About 300 adults aged 50 to 70 with this condition will receive either the herbal capsule or a placebo for 12 weeks. The main goal is to see if more patients achieve at least a 20% improvement in arthritis symptoms (ACR20) by the end of the study.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Kunxian Capsule (a traditional Chinese herbal medicine) combined with methotrexate and tofacitinib
- What this could lead to
- If effective, this combination could offer a new option for people with rheumatoid arthritis that does not respond well to standard treatments.
- What could go wrong
- This is a phase 4 trial, so the intervention is already in use, but its specific benefit over placebo in this combination is unproven. Herbal medicines can have side effects and interactions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
RECRUITINGShanghai, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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