New drug KPT-330 tested in kids with tough leukemia
NCT ID NCT02091245
First seen Jan 11, 2026 · Last updated May 14, 2026 · Updated 20 times
Summary
This study tests a drug called KPT-330 in children and teens (ages 1 to 21) with leukemia that has returned or not responded to standard treatments. The main goal is to find the safest dose and understand side effects. The drug works by blocking a protein that helps leukemia cells survive, potentially killing them. This is an early-phase trial with 16 participants.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Columbia University Medical Center
New York, New York, 10032, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Seattle Children's Hospital
Seattle, Washington, 98101, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
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UCSF
San Francisco, California, 94143, United States
Conditions
Explore the condition pages connected to this study.