Could a simple steroid taper ease pain after knee replacement?
NCT ID NCT05097976
First seen Apr 22, 2026 · Last updated Apr 29, 2026 · Updated 2 times
Summary
This study tests whether a short course of the steroid methylprednisolone, taken as pills after knee replacement surgery, can reduce pain, the need for strong painkillers, and nausea. About 420 adults having their first knee replacement will be randomly assigned to receive either the steroid or a placebo. The goal is to see if this approach leads to a smoother and less painful recovery in the first week and beyond.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Rush Oak Brook Outpatient Center
RECRUITINGOak Brook, Illinois, 60523, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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