Custom knee implants fail to prove superiority in halted study

NCT ID NCT02494544

Terminated Knowledge-focused Sponsor: Restor3D Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 28 times

Summary

This study aimed to see if a custom-made knee replacement (ConforMIS iTotal) helps patients move better than a standard off-the-shelf knee replacement. Researchers planned to enroll 215 adults with osteoarthritis who needed knee surgery. The study was stopped early, so results are limited.

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Contacts and locations

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Locations

Denver-Vail Orthopedics

Parker, Colorado, 80134, United States
OrthoNY

Albany, New York, 12205, United States
Sharp Healthcare

San Diego, California, 92123, United States
The Lindner Center for Research and Education

Cincinnati, Ohio, 45219, United States
Tufts University

Boston, Massachusetts, 02111, United States
University of California in San Diego

La Jolla, California, 92037, United States
University of Missouri

Columbia, Missouri, 65212, United States
Yale School of Medicine

New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.

OSTEOARTHRITIS