Freeze your pain away: new Pre-Surgery treatment aims to stop chronic knee pain before it starts

NCT ID NCT07425457

First seen Feb 20, 2026 · Last updated May 23, 2026 · Updated 10 times

Summary

This study tests whether freezing specific nerves around the knee (cryoneurolysis) at least 24 hours before total knee replacement surgery can reduce pain and improve function. About 100 adults with knee arthritis will be randomly assigned to receive either the freezing procedure plus surgery or surgery alone. Researchers will track pain levels and daily activities for 6 months to see if the freezing treatment leads to better long-term recovery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Attikon University General Hospital

    RECRUITING

    Athens, 12462, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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