Can this injection regrow knee cartilage?
NCT ID NCT05816395
First seen Feb 23, 2026 · Last updated May 15, 2026 · Updated 13 times
Summary
This study tested an experimental drug called RHH646 in 82 adults with knee osteoarthritis. The goal was to see if the drug could help regrow cartilage in the knee and check for any side effects. Participants received either the drug or a placebo, and changes in cartilage were measured using MRI scans.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Clinical Trial Network
Houston, Texas, 77074, United States
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Clinical Trials Research
Lincoln, California, 95648, United States
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Conquest Research
Winter Park, Florida, 32789, United States
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Novartis Investigative Site
Buenos Aires, C1055AAF, Argentina
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Novartis Investigative Site
Caba, C1015ABO, Argentina
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Novartis Investigative Site
Gandrup, 9362, Denmark
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Novartis Investigative Site
Herlev, 2730, Denmark
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Novartis Investigative Site
Warsaw, 00-874, Poland
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Novartis Investigative Site
Santiago, A Coruna, 15705, Spain
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Pioneer Research Solutions
Sugar Land, Texas, 77479, United States
Conditions
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