One-Shot knee injection tested for lasting arthritis pain relief

NCT ID NCT05449132

Completed Symptom relief Sponsor: Grünenthal GmbH Source: ClinicalTrials.gov ↗

Summary

This large, completed Phase 3 trial tested whether a single injection into the knee joint could safely reduce pain for people with osteoarthritis. It compared the experimental injection, called RTX-GRT7039, against a placebo (a dummy injection) in 466 adults whose knee pain wasn't fully helped by standard treatments. The main goal was to see if the injection provided better pain relief at 12 weeks and continued to help over a full year of observation.

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Contacts and locations

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Locations

Accellacare - Knoxville

Knoxville, Tennessee, 37912, United States
Accellacare Alcobendas

Madrid, 28100, Spain
Accellacare North London

Northwood, HA6 2RN, United Kingdom
Accellacare Research of Charlotte

Charlotte, North Carolina, 28209, United States
Accellacare Research of Winston Salem

Winston-Salem, North Carolina, 27103, United States
Accellacare South London

Orpington, BR5 3QG, United Kingdom
Accellacare of Raleigh

Raleigh, North Carolina, 27609, United States
Accellacare-Northamptonshire

Corby, Northamptonshire, NN18 9EZ, United Kingdom
Acclaim Clinical Research, Inc.

San Diego, California, 92120, United States
Achieve Clinical Research, LLC

Birmingham, Alabama, 35216, United States
Albuquerque Clinical Trials, Inc.

Albuquerque, New Mexico, 87102, United States
Allied Biomedical Research Institute

Miami, Florida, 33155, United States
Altoona Center for Clinical Research

Duncansville, Pennsylvania, 16635, United States
Antria Inc.

Indiana, Pennsylvania, 15701, United States
Arizona Arthritis and Rheumatology Associates (AARA) P.C

Glendale, Arizona, 85351, United States
Arthritis Group

Philadelphia, Pennsylvania, 19152-3303, United States
Arthroscopic Center, Copenhagen University Hospital

Amager, 2650, Denmark
Better Health Clinical Research, Inc.

Newnan, Georgia, 30265, United States
Chan Soon-Shiong Medical Center at Windber

Windber, Pennsylvania, 15963, United States
Charlottesville Medical Research Center LLC

Charlottesville, Virginia, 22911, United States
Chicago Clinical Research Institute Inc.

Chicago, Illinois, 60607, United States
Chicago Medical Research, LLC

Hazel Crest, Illinois, 60429, United States
Clinica Gaias

Santiago de Compostela, 15702, Spain
Clinical Neuroscience Solutions, Inc.

Orlando, Florida, 32806, United States
Clinical Neuroscience Solutions, Inc. dba CNS Healthcare

Orlando, Florida, 32801, United States
Coastal Carolina Research Center

North Charleston, South Carolina, 29405, United States
Complejo Hospitalario Universitario A Coruna

A Coruña, 15006, Spain
Complexo Hospitalario Universitario De Santiago De Compostela

Santiago de Compostela, 15706, Spain
Consorci Corporacio Sanitaria Parc Tauli

Sabadell, 08208, Spain
Core Health Care Group

Cerritos, California, 90703, United States
DelRicht Research

New Orleans, Louisiana, 70124, United States
Dr. Hans Richard Barthel, MD Office Of

Santa Barbara, California, 93108, United States
Drug Trials America

Hartsdale, New York, 10530, United States
Elite Clinical Studies, LLC

Phoenix, Arizona, 85018, United States
Excel Clinical Research

Las Vegas, Nevada, 89109, United States
Gastroenterology Associates of the Piedmont

Winston-Salem, North Carolina, 27103, United States
Glasgow Royal Infirmary - Greater Glasgow Health Board

Glasgow, G4 0SF, United Kingdom
Gulfcoast Research Institute

Sarasota, Florida, 34232, United States
Health Concepts

Rapid City, South Dakota, 57702, United States
Hospital CUF Porto

Porto, 4100-180, Portugal
Hospital Clinico Universitario De Santiago De Compostela

Santiago de Compostela, 15706, Spain
Hospital Dos Lusiadas Lisboa

Lisbon, 1500-458, Portugal
Hospital General Universitario de Elche

Elche, 03203, Spain
Hospital Quironsalud Infanta Luisa

Seville, 41010, Spain
Hospital Sanitas Cima

Barcelona, 08034, Spain
Hospital Universitario Virgen De La Arrixaca (Huva)

Murcia, 30120, Spain
Hospital Universitario Virgen de las Nieves

Granada, 18014, Spain
Hospital Universitario de La Princesa

Madrid, 28006, Spain
Hospital Universitaro De Elche

Elche, 7105, Spain
Hospital de Cascais

Alcabideche, 2755-009, Portugal
Injury Care Research

Boise, Idaho, 83713, United States
Institut d Investigacio i Innovacio Parc Tauli, Hospital Universitari Parc Tauli

Sabadell, 08208, Spain
June DO,PC

Lansing, Michigan, 48911, United States
LCMC Health Urgent Care - Lakeview

New Orleans, Louisiana, 70124, United States
Las Vegas Clinical Trials, LLC

North Las Vegas, Nevada, 89030, United States
MediSphere Medical Research Center, LLC

Evansville, Indiana, 47714, United States
Medvin Clinical Research

Thousand Oaks, California, 91360, United States
Neuroscience Research Center, LLC

Overland Park, Kansas, 66210, United States
Noble Clinical Research

Tucson, Arizona, 85704, United States
North Georgia Clinical Research

Woodstock, Georgia, 30189, United States
Oakland Medical Research Center

Troy, Michigan, 48085, United States
Orange County Research Institute

Anaheim, California, 92801, United States
PCPMG Clinical Research Unit, LLC

Greenville, South Carolina, 29601, United States
Park Road Medical Clinic

Charlotte, North Carolina, 28211, United States
Progressive Medical Research

Port Orange, Florida, 32127, United States
Raleigh Medical Group

Raleigh, North Carolina, 27609, United States
Robert Jones & Agnes Hunt Orthopaedic Hospital - Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust

Oswestry, Powys, SY10 7AG, United Kingdom
Royal Orthopaedic Hospital - Nhs Foundation Trust

Birmingham, B31 2AP, United Kingdom
Sensible Healthcare LLC

Ocoee, Florida, 34761, United States
Sundance Clinical Research, LLC

St Louis, Missouri, 63141, United States
The Center For Clinical Research

Winston-Salem, North Carolina, 27103, United States
The Parker Institute-Frederiksberg Hospital

Frederiksberg, 2000, Denmark
Tucson Orthopaedic Research Center

Tucson, Arizona, 85712, United States
University Orthopedics Center

Altoona, Pennsylvania, 16602, United States
University Orthopedics Center

Altoona, Pennsylvania, 9421166, United States
University Orthopedics Center

State College, Pennsylvania, 16801, United States
Upstate Clinical Research Associates

Williamsville, New York, 14221, United States
Vista Clinical Research

Newnan, Georgia, 30265, United States
Wasatch Clinical Research

Salt Lake City, Utah, 84107, United States
Well Pharma Medical Research, Corp.

Miami, Florida, 33173, United States
Westlake Medical Research

Thousand Oaks, California, 91360, United States

Conditions

Explore the condition pages connected to this study.

OSTEOARTHRITIS