New injection shows promise for aching knees

NCT ID NCT04636229

Summary

This study tested whether a single injection made from donated amniotic fluid could reduce pain and improve function in people with knee osteoarthritis. Over 500 adults who hadn't gotten enough relief from standard treatments received either the real injection or a placebo saline shot. Researchers tracked their knee pain, stiffness, and ability to do daily activities for a full year to see if the treatment was safe and effective.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AARDS Research, Inc.

    Aventura, Florida, 33180, United States

  • AMR Mobile

    Mobile, Alabama, 36608, United States

  • Actca, A Member of the Allliance Inc.

    Los Angeles, California, 90036, United States

  • Affinity Health

    Oak Brook, Illinois, 60523, United States

  • Affinity Health

    Nashville, Tennessee, 37203, United States

  • Alabama Clinical Therapeutics

    Birmingham, Alabama, 35235, United States

  • Arizona Arthritis & Rheumatology Research

    Glendale, Arizona, 85306, United States

  • Arizona Arthritis & Rheumatology Research

    Tucson, Arizona, 85704, United States

  • Cedar Health Research, LLC

    Burleson, Texas, 76028, United States

  • Central Research Associates

    Birmingham, Alabama, 35205, United States

  • Chicago Clinical Research Institute Inc

    Chicago, Illinois, 60607, United States

  • Coastal Carolina Research Center

    North Charleston, South Carolina, 29406, United States

  • Fiel Family & Sports Medicine/ CCT Research

    Tempe, Arizona, 85283, United States

  • Gulfcoast Research Institute

    Sarasota, Florida, 34232, United States

  • Horizon Clinical Research Center

    La Mesa, California, 91942, United States

  • Hospital for Special Surgery

    New York, New York, 10021, United States

  • Injury Care Research

    Boise, Idaho, 83713, United States

  • Klein & Associates, MD, PA

    Hagerstown, Maryland, 21740, United States

  • Lehigh Center for Clinical Research

    Allentown, Pennsylvania, 18104, United States

  • Lenox Hill Hospital (Northwell Health)

    New York, New York, 10075, United States

  • M3 Emerging Medical Research, LLC

    Durham, North Carolina, 27704, United States

  • M3 Emerging Medical Research, LLC

    Raleigh, North Carolina, 27612, United States

  • Methodist Physicians Clinic/ CCT Researc

    Fremont, Nebraska, 68025, United States

  • Moore Orthopedics and Sports Medicine

    Morehead City, North Carolina, 28557, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • PCPMG Clinical Research Unit, LLC

    Greenville, South Carolina, 29501, United States

  • Physician Research Collaboration

    Lincoln, Nebraska, 68516, United States

  • Pinnacle Trials, Inc.

    Stockbridge, Georgia, 30281, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • Sinai Hospital of Baltimore

    Baltimore, Maryland, 21215, United States

  • Spectrum Medical, Inc

    Danville, Virginia, 24541, United States

  • Stanford Medicine

    Redwood City, California, 94063, United States

  • Tri West Research Associates

    El Cajon, California, 92020, United States

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

  • University Orthopedic Center

    State College, Pennsylvania, 16801, United States

  • University Orthopedics Center

    Altoona, Pennsylvania, 16602, United States

  • University of California at Davis

    Sacramento, California, 95186, United States

  • University of California at Los Angeles

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.