Halted trial tests potential knee arthritis breakthrough

NCT ID NCT04814368

Summary

This study tested two experimental drugs, canakinumab and LNA043, given as injections directly into the knee joint of people with painful knee osteoarthritis. The goal was to see if these drugs could reduce pain, improve function, and potentially protect or even regrow knee cartilage. The trial was terminated early and only enrolled 23 participants, so results are very preliminary.

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Contacts and locations

Locations

  • Clinical Res Of W Florida

    Clearwater, Florida, 33765, United States

  • Horizon Clinical Research

    La Mesa, California, 91942, United States

  • LV Research

    Las Vegas, Nevada, 89119, United States

  • Lucas Research

    Morehead City, North Carolina, 28557, United States

  • Novartis Investigative Site

    Prague, Czech Republic, 19000, Czechia

  • Novartis Investigative Site

    Tartu, 50406, Estonia

  • Novartis Investigative Site

    Kecskemét, Bács-Kiskun county, 6044, Hungary

  • Novartis Investigative Site

    Budapest, 1036, Hungary

  • Novartis Investigative Site

    Riga, 1005, Latvia

  • Novartis Investigative Site

    Warsaw, 02-677, Poland

  • Precision Clinical Research LLC

    Sunrise, Florida, 33351, United States

Conditions

Explore the condition pages connected to this study.