Can an eye injection bring back light for the blind?
NCT ID NCT06628947
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tests an experimental drug called KIO-301, injected into the eye, for people with late-stage retinitis pigmentosa who have little or no light perception. The study will give up to three doses over several weeks to 36 participants to see if it is safe and can improve vision. It is a randomized, double-masked trial, meaning neither patients nor doctors know who gets the real drug versus a placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
KIO-301 (an experimental drug injected into the eye)
What this could lead to
If successful, this could point toward a treatment that restores some light perception in people with advanced retinitis pigmentosa.
What could go wrong
This is an early Phase 2 trial with only 36 participants, so results may not apply to everyone. The drug is injected directly into the eye, which carries risks like infection or inflammation.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cerulea Clinical Trials
RECRUITINGEast Melbourne, Victoria, 3002, Australia
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Lions Eye Institute
RECRUITINGNedlands, Western Australia, 6009, Australia
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Queensland Eye Institute
RECRUITINGWoolloongabba, Queensland, 4102, Australia
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Royal Adelaide Hospital
RECRUITINGAdelaide, South Australia, 5000, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Save Sight Institute
RECRUITINGSydney, New South Wales, 2000, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact