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Can an eye injection bring back light for the blind?

NCT ID NCT06628947

Recruiting now Disease control Sponsor: Kiora Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests an experimental drug called KIO-301, injected into the eye, for people with late-stage retinitis pigmentosa who have little or no light perception. The study will give up to three doses over several weeks to 36 participants to see if it is safe and can improve vision. It is a randomized, double-masked trial, meaning neither patients nor doctors know who gets the real drug versus a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
KIO-301 (an experimental drug injected into the eye)
What this could lead to
If successful, this could point toward a treatment that restores some light perception in people with advanced retinitis pigmentosa.
What could go wrong
This is an early Phase 2 trial with only 36 participants, so results may not apply to everyone. The drug is injected directly into the eye, which carries risks like infection or inflammation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

retinitis pigmentosa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RETINITIS PIGMENTOSA

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Cerulea Clinical Trials

    RECRUITING

    East Melbourne, Victoria, 3002, Australia

  • Lions Eye Institute

    RECRUITING

    Nedlands, Western Australia, 6009, Australia

  • Queensland Eye Institute

    RECRUITING

    Woolloongabba, Queensland, 4102, Australia

  • Royal Adelaide Hospital

    RECRUITING

    Adelaide, South Australia, 5000, Australia

  • Save Sight Institute

    RECRUITING

    Sydney, New South Wales, 2000, Australia

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