Two drugs better than one for Kids' lung pressure?

NCT ID NCT04039464

Completed Disease control Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

Summary

This study tested whether starting children with pulmonary arterial hypertension on two oral medications (sildenafil and bosentan) together works better than starting with just one (sildenafil alone). It involved 28 children and teenagers with moderate symptoms, aiming to see which approach improved their ability to perform daily activities over 12 months. The goal was to find the best initial treatment strategy to control this serious lung and heart condition.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Baylor College of Medicine

Houston, Texas, 77030, United States
Boston Children's Hospital

Boston, Massachusetts, 02115, United States
Children's Hospital Colorado

Aurora, Colorado, 80045, United States
Columbia University Medical Center

New York, New York, 10032, United States
Johns Hopkins All Children's Hospital

St. Petersburg, Florida, 33701, United States
Johns Hopkins Medical Institutions

Baltimore, Maryland, 21287, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
New York Medical College

Valhalla, New York, 10595, United States
Seattle Children's Hospital

Seattle, Washington, 98105, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.

PEDIATRIC PULMONARY HYPERTENSION