New drug combo aims to stop silent kidney transplant failure before it starts

NCT ID NCT06291103

Summary

This study is testing whether switching kidney transplant patients from standard anti-rejection drugs to a newer drug called belatacept can better control early, silent rejection. Researchers will enroll 290 adult kidney transplant recipients who develop certain antibodies but show no symptoms of rejection yet. The goal is to treat rejection earlier to prevent long-term kidney damage and transplant failure.

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