Tailored drug cocktail may improve kidney transplant success

NCT ID NCT07633600

First seen Jun 11, 2026 · Last updated Jun 23, 2026 · Updated 2 times

Summary

This study tests whether giving specific blood pressure drugs based on real-time heart and vessel measurements can improve fluid management during kidney transplant surgery. Researchers will assign 255 adults to receive vasopressin, norepinephrine, calcium chloride, or dopamine depending on their circulation type. The goal is to see if this personalized approach leads to better responses to intravenous fluids.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vasopressin, Norepinephrine, Calcium Chloride, Dopamine

What this could lead to

If it works, this could lead to better fluid management during kidney transplants, potentially improving outcomes and reducing complications.

What could go wrong

This is a Phase 4 trial that has not yet started recruiting. The approach is highly specific to the operating room and may not translate to broader benefits. Risks include side effects from the vasoactive drugs.

Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.