New drug combo could slash Years-Long wait for kidney transplants

NCT ID NCT05017545

First seen Feb 28, 2026 · Last updated May 13, 2026 · Updated 11 times

Summary

This study tests whether two drugs, carfilzomib and belatacept, can lower the immune sensitivity of kidney transplant candidates who are highly sensitized—meaning their bodies reject most donor kidneys. The goal is to make it easier and quicker to find a compatible donor. About 21 participants with end-stage kidney disease will receive the drugs and be monitored for safety and effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Duke Transplant Center, Duke University Medical Center

    Durham, North Carolina, 27710, United States

Conditions

Explore the condition pages connected to this study.