Kidney health may change how body handles cancer drug

NCT ID NCT05469100

First seen Nov 01, 2025 · Last updated May 30, 2026 · Updated 32 times

Summary

This study looked at how the drug selpercatinib moves through the body in people with different levels of kidney function. It included 37 adults, some healthy and some with kidney problems. The goal was to see how kidney impairment changes drug levels and clearance, helping doctors adjust doses in the future.

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Contacts and locations

Locations

  • Anaheim Regional Center

    Anaheim, California, 92801, United States

  • Clinical Pharmacology of Miami

    Miami, Florida, 33014, United States

  • Orange County Research Center

    Tustin, California, 92780, United States

  • Orlando Clinical Research Center

    Orlando, Florida, 32809, United States

  • Riverside Clinical Research

    Edgewater, Florida, 32132, United States

  • Stanford Health Care, Valley Care Program

    Pleasanton, California, 94588, United States

Conditions

Explore the condition pages connected to this study.