Kidney Health's impact on cancer drug tested in small trial
NCT ID NCT05469100
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 27 times
Summary
This early-phase study aimed to understand how kidney function affects how the body processes the cancer drug LOXO-292 (selpercatinib). Researchers compared 37 participants—some with healthy kidneys and some with varying degrees of kidney impairment—after giving them a single dose. The goal was to measure how much drug entered the bloodstream and how long it stayed, to help determine safe dosing for future patients with kidney problems.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Anaheim Regional Center
Anaheim, California, 92801, United States
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Clinical Pharmacology of Miami
Miami, Florida, 33014, United States
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Orange County Research Center
Tustin, California, 92780, United States
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Orlando Clinical Research Center
Orlando, Florida, 32809, United States
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Riverside Clinical Research
Edgewater, Florida, 32132, United States
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Stanford Health Care, Valley Care Program
Pleasanton, California, 94588, United States
Conditions
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