Two-Drug combo vs. single drug: major trial aims to improve survival for Tough-to-Treat kidney cancer

NCT ID NCT03873402

Ongoing Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a combination of two immunotherapy drugs (nivolumab and ipilimumab) works better than just one of them (nivolumab alone) for people with advanced kidney cancer that has spread. It involves 437 adults with newly diagnosed, aggressive forms of the disease. The main goal is to see which treatment better controls the cancer and keeps it from growing.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Local Institution - 0001

Viedma, Río Negro Province, R8500ACE, Argentina
Local Institution - 0002

San Juan, 5400, Argentina
Local Institution - 0003

Santiago, Santiago Metropolitan, 8330024, Chile
Local Institution - 0004

Viña del Mar, Región de Valparaíso, 2520598, Chile
Local Institution - 0005

Córdoba, X5004FHP, Argentina
Local Institution - 0006

Mexico City, Mexico City, 06100, Mexico
Local Institution - 0008

Chihuahua City, 31000, Mexico
Local Institution - 0009

Mexico City, Mexico City, 14080, Mexico
Local Institution - 0010

Mexico City, Mexico City, 14080, Mexico
Local Institution - 0011

Ciudad Autónoma de Buenos Aires, Buenos Aires, 1280, Argentina
Local Institution - 0012

Viña El Mar, Región de Valparaíso, 254 0488, Chile
Local Institution - 0013

Washington D.C., District of Columbia, 20007, United States
Local Institution - 0014

Arezzo, 52100, Italy
Local Institution - 0015

Parma, 43100, Italy
Local Institution - 0016

Aviano (PN), 33081, Italy
Local Institution - 0017

Independencia, Santiago Metropolitan, Chile
Local Institution - 0018

Prague, 140 59, Czechia
Local Institution - 0019

Prague, 100 34, Czechia
Local Institution - 0020

Brno, South Moravian, 602 00, Czechia
Local Institution - 0021

Milan, 20141, Italy
Local Institution - 0023

Athens, 15125, Greece
Local Institution - 0024

Larissa, 41110, Greece
Local Institution - 0025

Río Cuarto, Córdoba Province, 5800, Argentina
Local Institution - 0026

Gdansk, 80-219, Poland
Local Institution - 0027

Warsaw, 02-781, Poland
Local Institution - 0029

Poznan, 61-848, Poland
Local Institution - 0030

Biała Podlaska, 21-500, Poland
Local Institution - 0031

Vienna, 1090, Austria
Local Institution - 0032

Wels, 4600, Austria
Local Institution - 0033

Graz, 8036, Austria
Local Institution - 0034

Santiago, Santiago Metropolitan, 8420383, Chile
Local Institution - 0035

Madrid, 28046, Spain
Local Institution - 0036

Madrid, 28034, Spain
Local Institution - 0037

Barcelona, 08035, Spain
Local Institution - 0038

Barcelona, 08003, Spain
Local Institution - 0039

Sabadell, 08208, Spain
Local Institution - 0040

Valencia, 46009, Spain
Local Institution - 0041

Seville, 41013, Spain
Local Institution - 0042

Córdoba, 14004, Spain
Local Institution - 0043

Santander, 39008, Spain
Local Institution - 0044

Santiago Compostela, 15706, Spain
Local Institution - 0045

Pamplona, 31008, Spain
Local Institution - 0046

Querétaro, 76000, Mexico
Local Institution - 0050

Lisbon, 1649-035, Portugal
Local Institution - 0053

Athens, Georgia, 30607, United States
Local Institution - 0054

Saint Petersburg, Sankt-Peterburg, 194044, Russia
Local Institution - 0056

Cluj-Napoca, 400015, Romania
Local Institution - 0058

Novosibirsk, 630099, Russia
Local Institution - 0060

Mar del Plata, Buenos Aires, 7600, Argentina
Local Institution - 0061

Bucharest, 020122, Romania
Local Institution - 0062

Bytom, 41-902, Poland
Local Institution - 0065

Craiova, 200542, Romania
Local Institution - 0066

Boston, Massachusetts, 02114, United States
Local Institution - 0067

Monterrey, Nuevo León, 64040, Mexico
Local Institution - 0068

Villejuif, 94800, France
Local Institution - 0069

Angers, 49100, France
Local Institution - 0071

Marseille, 13273, France
Local Institution - 0072

Suresnes, 92151, France
Local Institution - 0073

Angers, 49055, France
Local Institution - 0074

Brest, Finistère, 29609, France
Local Institution - 0075

Besançon, 25030, France
Local Institution - 0077

Roma, 00128, Italy
Local Institution - 0078

Nancy, Meurthe-et-Moselle, 54100, France
Local Institution - 0080

La Tronche, 38043, France
Local Institution - 0081

Hyères, 83400, France
Local Institution - 0082

Brescia, Lombardy, 25123, Italy
Local Institution - 0084

Charleston, South Carolina, 29414, United States
Local Institution - 0086

Boston, Massachusetts, 02215, United States
Local Institution - 0088

Boston, Massachusetts, 02114, United States
Local Institution - 0091

Valenciennes, Nord, 59300, France
Local Institution - 0092

Paris, 75014, France
Local Institution - 0093

Strasbourg, 67091, France
Local Institution - 0094

Caen, 14076, France
Local Institution - 0095

Bydgoszcz, 85-796, Poland
Local Institution - 0096

Nice, Alpes-Maritimes, 06189, France
Local Institution - 0097

Brno, 656 53, Czechia
Local Institution - 0100

Capital Federal, Buenos Aires, 1419, Argentina
The Reading Hosp Med Ctr Reg Cancer Ctr

West Reading, Pennsylvania, 19611, United States

Conditions

Explore the condition pages connected to this study.

RENAL CELL CARCINOMA