Ketone drink study reveals surprising effects on blood hormones

NCT ID NCT06053138

Completed Knowledge-focused Sponsor: Central Jutland Regional Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study with 16 healthy adults tested how a ketone supplement affects beta-hydroxybutyrate (BHB) levels and erythropoietin (EPO), a hormone that controls red blood cell production. Participants took either the ketone drink or a placebo for two weeks. Researchers measured BHB from different blood sampling sites and checked EPO, estradiol, and ferritin levels. The goal was to understand ketosis effects on these markers, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ketone monoester dietary supplement
What this could lead to: If successful, this could help researchers understand how ketosis influences erythropoietin and hormone levels, potentially guiding future studies on metabolic health.
What could go wrong: This is a small, early-stage study with only 16 healthy participants, so results may not apply to broader populations or have direct clinical impact.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Ketosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KETOSIS

Contacts and locations

Locations

Department of Internal Medicine, Viborg Regional Hospital

Viborg, 8800, Denmark

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