New study aims to break the Pain-to-Opioid cycle after trauma

NCT ID NCT06201676

Summary

This study is testing if a short, 5-day course of a common anti-inflammatory drug (ketorolac) given right after major bone surgery can help prevent patients from needing opioid painkillers long-term. It will enroll 458 adults with serious orthopedic injuries. Researchers will compare patients who get the drug plus standard pain care to those who get standard care alone, checking opioid use and pain-related function for 6 months.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.