Could a ketone drink ease alcohol withdrawal?
NCT ID NCT06559995
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether a ketone supplement drink can reduce alcohol withdrawal symptoms in 30 adults with moderate to severe alcohol use disorder. Participants will receive either the ketone drink or a placebo for 4 days during inpatient detox. The main goal is to see if the ketone drink lowers the amount of benzodiazepine medication needed to manage withdrawal.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketone supplement (D-beta-hydroxybutyric acid and R-1,3 butanediol)
What this could lead to
If it works, this could offer a new way to manage alcohol withdrawal symptoms and reduce reliance on standard sedative medications.
What could go wrong
This is an early combined Phase 2/3 trial with only 30 participants, so results may not apply broadly. The supplement may not outperform placebo, and side effects are not yet well understood.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Center for Studies of Addiction
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••