Can a simple alarm prevent a dangerous complication in type 1 diabetes?

NCT ID NCT07225465

First seen Nov 06, 2025 · Last updated May 01, 2026 · Updated 18 times

Summary

This study tests whether using a lower ketone alarm level (1.0 vs 1.5 mmol/L) can help people with type 1 diabetes safely take dapagliflozin, a drug that lowers blood sugar but raises the risk of diabetic ketoacidosis (DKA). 115 adults will wear a continuous ketone monitor and be randomly assigned to one of two alarm thresholds. The goal is to find the best way to catch rising ketones early and prevent DKA, potentially making this drug safer for type 1 diabetes.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Austin Health

    Heidelberg, Victoria, 3084, Australia

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Baker Heart and Diabetes Institute

    Melbourne, Victoria, 3004, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St Vincent's Hospital Melbourne

    Fitzroy, Victoria, 3065, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Royal Melbourne Hospital

    Parkville, Victoria, 3050, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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