Keto diet may supercharge cancer immunotherapy, early trial hints
NCT ID NCT07564219
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether raising blood levels of a natural molecule called beta-hydroxybutyrate (BHB) — through a strict ketogenic diet or ketone drinks — is safe and can improve the effectiveness of immunotherapy (CAR-T cells or bispecific antibodies) in 45 adults with multiple myeloma. Participants are randomly assigned to one of four intervention groups or a control group for 28 days. The goal is to see if this metabolic boost can enhance T-cell function without causing severe side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ketogenic diet and ketone monoester supplements
- What this could lead to
- If successful, this could show that raising BHB levels safely enhances T-cell function, potentially improving outcomes for multiple myeloma patients on immunotherapy.
- What could go wrong
- This is an early, small study (45 participants) testing feasibility and safety, not efficacy. The diet or supplements may be hard to tolerate, and results may not lead to better cancer control.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Medical Center Hamburg-Eppendorf
RECRUITINGHamburg, Free and Hanseatic City of Hamburg, 20251, Germany
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