Keto diet may supercharge cancer immunotherapy, early trial hints

NCT ID NCT07564219

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether raising blood levels of a natural molecule called beta-hydroxybutyrate (BHB) — through a strict ketogenic diet or ketone drinks — is safe and can improve the effectiveness of immunotherapy (CAR-T cells or bispecific antibodies) in 45 adults with multiple myeloma. Participants are randomly assigned to one of four intervention groups or a control group for 28 days. The goal is to see if this metabolic boost can enhance T-cell function without causing severe side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ketogenic diet and ketone monoester supplements

What this could lead to

If successful, this could show that raising BHB levels safely enhances T-cell function, potentially improving outcomes for multiple myeloma patients on immunotherapy.

What could go wrong

This is an early, small study (45 participants) testing feasibility and safety, not efficacy. The diet or supplements may be hard to tolerate, and results may not lead to better cancer control.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • University Medical Center Hamburg-Eppendorf

    RECRUITING

    Hamburg, Free and Hanseatic City of Hamburg, 20251, Germany

    Contact Email: •••••@•••••