Could a High-Fat diet replace drugs for kids with absence seizures?

NCT ID NCT04274179

First seen May 07, 2026

Summary

This study tests whether a modified Atkins diet (low carb, high fat) can control seizures in children aged 3-12 with newly diagnosed absence epilepsy, without using standard medications. Forty children will be enrolled and compared to a group whose parents chose medication instead. The goal is to see if the diet is a feasible and effective first-line treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Modified Atkins diet (low-carb, high-fat, moderate protein)

What this could lead to

If successful, this diet could offer a drug-free option to control seizures in children newly diagnosed with absence epilepsy.

What could go wrong

This is a small, early-stage trial with only 40 participants, and the diet is restrictive, which may be hard for children to follow long-term. It may not work as well as standard medications.

Conditions

The condition(s) this trial relates to.

childhood absence epilepsy Epilepsy, Absence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.