Keto diet cholesterol mystery: scientists investigate
NCT ID NCT06894004
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at why very-low-carb ketogenic diets can cause high cholesterol in some normal-weight people. Researchers will enroll 100 adults, identify those whose cholesterol spikes on keto, and measure how their bodies make and remove cholesterol-carrying particles. The goal is to understand the mechanism behind this effect, not to test a treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ketogenic Diet
- What this could lead to
- If successful, this could explain why some people get high cholesterol on keto diets, potentially guiding safer diet recommendations.
- What could go wrong
- This is a small, early-stage observational study focused on understanding mechanisms, not testing a treatment. Results may not apply to everyone or lead to immediate changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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