New nasal spray aims to quickly ease depression and suicidal urges

NCT ID NCT07193901

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 24 times

Summary

This study tests a new nasal spray called PRT-042 (a form of ketamine) to see if it can quickly reduce depression and suicidal thoughts in adults with major depressive disorder. About 98 participants will receive either the spray or a placebo. The main goal is to measure changes in depression symptoms 24 hours after the first dose. The study is currently recruiting.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BEIjing AnDing hospital capital medical university

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing AnDing hospital capital medical university

    RECRUITING

    Beijing, China

    Contact

  • Beijing Huilongguan Hospital

    RECRUITING

    Beijing, China

    Contact

  • Hangzhou Seventh People's Hospital

    RECRUITING

    Hangzhou, China

    Contact

    Contact

  • Suzhou Guangji Hospital

    RECRUITING

    Suzhou, China

    Contact

  • The Fourth People's Hospital of Chengdu

    RECRUITING

    Chengdu, China

    Contact

  • The affiliated Kangning Hospital of Ningbo University

    RECRUITING

    Ningbo, China

    Contact

  • The fourth affiliated hospital of Anhui medical university

    RECRUITING

    Hefei, China

    Contact

Conditions

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