Could ketamine boost recovery for critically ill patients on ventilators?

NCT ID NCT07590687

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding low-dose ketamine to standard sedatives helps critically ill patients on breathing machines recover faster and spend more days alive at home. About 640 adults who need unplanned ventilation and sedation will receive either ketamine or a placebo for up to 14 days. Researchers will track outcomes like days at home, brain function, and side effects for 90 days.

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Conditions

The condition(s) this trial relates to.

Critical Illness delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Intensive Care Medicine, APHP.Nord, hôpital Bichat Claude Bernard,

    Paris, 75018, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Other studies related to the condition(s) this trial covers.