Could a single ketamine dose lift depression in veterans with Parkinson's?

NCT ID NCT06231563

First seen Mar 22, 2026 · Last updated Apr 24, 2026 · Updated 4 times

Summary

This study is testing whether a single intravenous dose of ketamine can quickly improve depression in 80 veterans with Parkinson's disease who haven't responded well to standard antidepressants. Researchers will also look at how ketamine affects the brain's ability to adapt and levels of inflammation. The goal is to find a new, fast-acting treatment option for a common and disabling symptom in Parkinson's.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • San Francisco VA Medical Center, San Francisco, CA

    RECRUITING

    San Francisco, California, 94121-1563, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.