Can a common anesthetic protect young brains during heart surgery?

NCT ID NCT06525584

NEW Recruiting now Disease control Sponsor: Kemerovo State Medical University Source: ClinicalTrials.gov ↗

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This trial asks whether giving children a low-dose ketamine infusion after heart surgery can protect their brains from damage. Children aged 1 to 60 months undergoing surgery for certain congenital heart defects will receive either ketamine at one of two doses or no ketamine. Researchers will monitor blood markers of brain injury at several points to see if ketamine makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ketamine infusion at a low dose for 16 hours after surgery
What this could lead to: If it works, this could point toward a simple way to reduce brain injury in children after heart surgery, potentially improving their recovery and long-term development.
What could go wrong: This is an early-stage trial, and the results may not show a clear benefit. Ketamine can have side effects, and the study is limited to a specific group of children and heart defects.

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Conditions

The condition(s) this trial relates to.

atrial septal defect brain injury ventricular septal defect

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN INJURIES

Contacts and locations

Locations

Artem Ivkin
RECRUITING

Kemerovo, Please Select, 650066, Russia

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