New antibody KBA1412 tested in patients with Hard-to-Treat cancers

NCT ID NCT05501821

First seen Sep 30, 2025 · Last updated May 20, 2026 · Updated 30 times

Summary

This early-phase trial tested a new drug called KBA1412, a lab-made antibody that targets a protein on cancer cells. It was given alone or with another cancer drug (pembrolizumab) to 16 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety and see if the drug could shrink tumors.

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Contacts and locations

Locations

  • Dutch Cancer Institute AVL

    Amsterdam, 1066 CX, Netherlands

  • Erasmus Medical Center Rotterdam

    Rotterdam, 3015 GD, Netherlands

  • University Hospital Antwerp

    Antwerp, 2650, Belgium

  • University Hospital Ghent

    Ghent, 9000, Belgium

  • University Hospital Leiden (LUMC)

    Leiden, 2333 ZA, Netherlands

Conditions

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