New antibody shows promise in early cancer trial

NCT ID NCT05501821

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested a new drug called KBA1412, a lab-made antibody that targets a protein on cancer cells. It was given alone or with another cancer drug (pembrolizumab) to 16 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety and see if the drug could shrink tumors.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dutch Cancer Institute AVL

    Amsterdam, 1066 CX, Netherlands

  • Erasmus Medical Center Rotterdam

    Rotterdam, 3015 GD, Netherlands

  • University Hospital Antwerp

    Antwerp, 2650, Belgium

  • University Hospital Ghent

    Ghent, 9000, Belgium

  • University Hospital Leiden (LUMC)

    Leiden, 2333 ZA, Netherlands

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