New drug shows promise for controlling severe schizophrenia symptoms

NCT ID NCT05919823

Summary

This study tested a medication called KarXT for adults in China who were hospitalized due to a severe worsening of schizophrenia symptoms. For the first 5 weeks, some participants received the drug while others received a placebo, and neither they nor their doctors knew which. Then, all participants could receive KarXT for another 12 weeks. The main goal was to see if KarXT safely reduced the overall severity of schizophrenia symptoms, like hallucinations and social withdrawal, compared to a placebo.

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Contacts and locations

Locations

  • Anhui Mental Health Center

    Hefei, Anhui, 230022, China

  • Beijing Anding Hospital Capital Medical University

    Beijing, Beijing Municipality, 100035, China

  • Beijing HuiLongGuan Hospital

    Changping, Beijing Municipality, 100096, China

  • Chongqing 11th People's Hospital

    Chongqing, Chongqing Municipality, 400047, China

  • Chongqing Mental Health Center

    Jiangbei, Chongqing Municipality, 401147, China

  • Daqing City Third Hospital

    Daqing, Heilongjiang, 163161, China

  • Guangyuan Mental Health Center

    Guangyuan, Sichuan, 628033, China

  • Hangzhou Seventh People's Hospital

    Hangzhou, Zhejiang, 310013, China

  • HuZhou Third Municipal Hospital

    Huzhou, Zhejiang, 313028, China

  • Jiangxi Mental Health Center

    Nanchang, Jiangxi, 330027, China

  • Mental Health Center of Xi'an City

    Xi'an, Shaanxi, 710061, China

  • Ningbo Kangning Hospital

    Ningbo, Zhejiang, 315002, China

  • Peking University Sixth Hospital

    Beijing, Beijing Municipality, 100083, China

  • Renmin Hospital of Wuhan University

    Wuhan, Hubei, 430064, China

  • Shandong Daizhuang Hospital

    Jining, Shandong, 272009, China

  • Shandong Mental Health Center

    Jinan, Shandong, 250014, China

  • Shanghai Mental Health Center

    Shanghai, Shanghai Municipality, 200032, China

  • The Affiliated Brain Hospital of Guangzhou Medical University

    Guanzhou, Guangdong, 510370, China

  • The First Affiliated Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, 325015, China

  • The Fourth People's Hospital of Chengdu

    Chengdu, Sichuan, 610036, China

  • The Second Xiangya Hospital of Central South University

    Changsha, Hunan, 410011, China

  • The Sixth People's Hosptial of Hebei Province

    Baoding, Hebei, 071051, China

  • Tianjin Anding Hospital

    Tianjin, Tianjin Municipality, 300382, China

  • Urumqi Fourth People's Hospital

    Ürümqi, Xinjiang, 830002, China

  • Wuhan Mental Health Center

    Wuhan, Hubei, 430000, China

  • Wuhu Hospital of Beijing Anding Hospital

    Wuhu, Anhui, 241000, China

  • Wuxi Mental Health Center

    Wuxi, Jiangsu, 214151, China

  • Zhumadian Second People's Hospital

    Zhumadian, Henan, 463001, China

Conditions

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