Karuna Therapeutics

This study is testing whether a medication called KarXT can safely reduce distressing psychosis symptoms like hallucinations and delusions in people with Alzheimer's disease. It will involve about 406 adults aged 55-90 who have been diagnosed with Alzheimer's and have experienced…

This study follows people with Alzheimer's disease who experience psychosis (like hallucinations or delusions) to see how safe a medication called KarXT is when taken for a full year. It's for 800 people who have already completed one of three earlier KarXT studies. The main goal…

This study aims to understand how a new drug called KarXT changes the way the body processes three other common medications: midazolam (a sedative), fexofenadine (an allergy medicine), and digoxin (a heart medicine). It will involve 60 healthy adult volunteers. Researchers will m…

This study aims to measure how much KarXT medication passes into breast milk when taken by healthy nursing mothers. Researchers will track medication levels in both breast milk and blood over time to understand potential infant exposure. The study involves 8 healthy lactating par…

This study aims to understand how a person's genetic makeup affects how their body processes an experimental drug called KarXT. Researchers will enroll 56 healthy adults who have different genetic profiles related to drug metabolism. The main goal is to measure drug levels in the…