New drug shields celiac patients from gluten damage in early trial

NCT ID NCT06001177

First seen Jan 05, 2026 · Last updated May 05, 2026 · Updated 18 times

Summary

This study tested an experimental drug called KAN-101 in 55 adults with celiac disease who had been on a gluten-free diet for at least a year. The goal was to see if the drug could reduce damage to the small intestine caused by a two-week gluten challenge. Results suggested KAN-101 helped protect the gut lining compared to a placebo, but more research is needed to confirm long-term safety and effectiveness.

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Contacts and locations

Locations

  • Albert Schweitzer Ziekenhuis, locatie Dordwijk

    Dordrecht, South Holland, 3318AT, Netherlands

  • Alliance for Multispecialty Research, LLC

    Wichita, Kansas, 67207, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • CRST Helsinki Oy

    Helsinki, Uusimaa, 00180, Finland

  • Centre Intégré de Santé et de Services Sociaux-Chaudière Appalaches - Hôtel-Dieu de Lévis

    Lévis, Quebec, G6V 3Z1, Canada

  • Centrum Medyczne Med-Gastr Sp. z o.o.

    Lodz, Łódź Voivodeship, 91-034, Poland

  • Clinical Research Services Turku

    Turku, Southwest Finland, 20520, Finland

  • Connolly Hospital

    Dublin, Dublin, D15X40D, Ireland

  • Diex Recherche Quebec Inc.

    Québec, Quebec, G1V 4T3, Canada

  • Gastromed Sp. z o. o.

    Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland

  • Homestead Associates in Research Inc.

    Miami, Florida, 33032, United States

  • Hopital Du Sacre-Coeur De Montreal

    Montreal, Quebec, H4J 1C5, Canada

  • LHSC

    London, Ontario, N6A 5W9, Canada

  • MZ Badania Slowik Zymla Spolka Jawna

    Knurów, Silesian Voivodeship, 44-190, Poland

  • McMaster University

    Hamilton, Ontario, L8S 4L8, Canada

  • Melita Medical

    Wroclaw, Lower Silesian Voivodeship, 50-449, Poland

  • Midland Regional Hospital Mullingar

    Mullingar, Westmeath, N91Na43, Ireland

  • Ochsner Clinic Foundation

    New Orleans, Louisiana, 70121, United States

  • Our Lady of Lourdes Hospital

    Drogheda, Louth, A92VW28, Ireland

  • Peak Gastroenterology Associates

    Colorado Springs, Colorado, 80907, United States

  • Rabin Medical Center

    Petah Tikva, Central District, 4941492, Israel

  • Shaare Zedek Medical Center

    Jerusalem, Jerusalem, 9103102, Israel

  • Sheba Medical Center

    Ramat Gan, Central District, 5265601, Israel

  • Soroka Medical Center

    Beersheba, Southern District, 8410101, Israel

  • Studiengesellschaft BSF Unternehmergesellschaft

    Halle, Saxony-Anhalt, 6108, Germany

  • Tays Research Services

    Tampere, Pirkanmaa, 33520, Finland

  • Unlimited Medical Research Group

    Hialeah Gardens, Florida, 33018, United States

  • WIP Warsaw IBD Point Profesor Kierkuś

    Warsaw, Masovian Voivodeship, 00-728, Poland

Conditions

Explore the condition pages connected to this study.