Cure My Disease

Don't miss your cure!

 Log in / Sign up

New hope for kids with psoriatic arthritis: drug combo under trial

NCT ID NCT05083182

Completed Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This study is testing two injectable drugs, ustekinumab and guselkumab, in 50 children with active juvenile psoriatic arthritis. The goal is to see how well the drugs work, how they move through the body, and if they are safe. Participants will receive one of the drugs and be monitored for about a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ustekinumab and guselkumab (biologic drugs given as injections)
What this could lead to
If successful, this study could show that these drugs are safe and effective for children with juvenile psoriatic arthritis, offering a new treatment option.
What could go wrong
This is an early-phase study with only 50 children, so results may not apply to everyone. The drugs can have side effects like increased risk of infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ARTHRITIS, JUVENILE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

juvenile idiopathic arthritis psoriasis-related juvenile idiopathic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHRITIS, JUVENILE

Contacts and locations

Locations

  • Aarhus Universitetshospital

    Aarhus, 8200, Denmark

  • Asklepios Klinik Sankt Augustin

    Sankt Augustin, 53757, Germany

  • Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia Presidio Spedali Civili

    Brescia, 25100, Italy

  • CHU de Caen

    Caen, 14033, France

  • CHU de Toulouse Hopital des Enfants

    Toulouse, 31059, France

  • CSK, Uniwersyteckie Centrum Pediatrii im.M.Konopnickiej

    Lodz, 91-738, Poland

  • Centro Medico Privado de Reumatologia

    San Miguel de Tucumán, T4000AXL, Argentina

  • Centro Specialistico Ortopedico Traumatologico Gaetano Pini CTO

    Milan, 20122, Italy

  • Centrum Zdrowia Dziecka i Rodziny im Jana Pawla II w Sosnowcu Sp z o o

    Sosnowiec, 41 200, Poland

  • Charite Universitatsmedizin Berlin Campus Virchow Klinikum

    Berlin, 13353, Germany

  • Childrens Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico

    Milan, 20122, Italy

  • Great Ormond Street Hospital

    London, WC1N 3JH, United Kingdom

  • Hacettepe Universitesi Hastanesi

    Ankara, 6230, Turkey (Türkiye)

  • Harvard Medical School - Boston Children's Hospital

    Boston, Massachusetts, 02215-5450, United States

  • Haywood Hospital

    Staffordshire, ST6 7AG, United Kingdom

  • Hopital Nord Marseille

    Marseille, 13015, France

  • Hopital de Bicetre

    Le Kremlin-Bicêtre, 94270, France

  • Hosp Reina Sofia

    Córdoba, 14004, Spain

  • Hosp Univ Vall D Hebron

    Barcelona, 08035, Spain

  • Hosp. Clinico Univ. de Santiago

    Santiago de Compostela, 15706, Spain

  • Hosp. Infanta Luisa

    Seville, 41010, Spain

  • Hosp. Univ. I Politecni La Fe

    Valencia, 46026, Spain

  • Hosp. de La Santa Creu I Sant Pau

    Barcelona, 8041, Spain

  • Hospital de Ninos de Cordoba

    Córdoba, 5000, Argentina

  • Hôpital D'Enfants

    Vandœuvre-lès-Nancy, 54511, France

  • IRCCS Ospedale Pediatrico Bambino Gesu

    Roma, 00165, Italy

  • Instituto Caici

    Rosario, S2000PBJ, Argentina

  • Instituto Medico Platense

    La Plata, B1900, Argentina

  • Istanbul University Cerrahpasa Medical Faculty

    Istanbul, 34098, Turkey (Türkiye)

  • Istituto Giannina Gaslini

    Genova, 16147, Italy

  • Kocaeli University Medical Faculty

    Kocaeli, 41380, Turkey (Türkiye)

  • Legacy Emanuel Medical Center

    Portland, Oregon, 97227, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467-2403, United States

  • Narodowy Instytut Geriatrii Reumatologii i Rehabilitacji im prof dr hab med Eleonory Reicher

    Warsaw, 02 637, Poland

  • Northwell Health

    New York, New York, 11040, United States

  • Nottingham University Hospitals NHS Trust

    Nottingham, NG7 2UH, United Kingdom

  • Odense Universitets Hospital

    Odense, 5000, Denmark

  • Royal Manchester Children's Hospital

    Manchester, M13 9WL, United Kingdom

  • Royal Stoke University Hospital

    Stoke-on-Trent, ST4 6QG, United Kingdom

  • Royal Victoria Infirmary

    Newcastle upon Tyne, NE1 4LP, United Kingdom

  • STAT Research S A

    Ciudad Autonoma Buenos Aires, C1013AAAB, Argentina

  • Schon Klinik Hamburg Eilbek

    Hamburg, 22081, Germany

  • Sheffield Children's Hospital

    Sheffield, S10 2TH, United Kingdom

  • Southampton General Hospital

    Southampton, SO16 6YD, United Kingdom

  • UCLA

    Los Angeles, California, 90095-3075, United States

  • Umraniye Training and Research Hospital

    Istanbul, 34766, Turkey (Türkiye)

  • University of North Carolina

    Chapel Hill, North Carolina, 27514, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.