Blood samples may unlock secrets of a common epilepsy
NCT ID NCT03400371
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study aims to find the genetic causes of juvenile myoclonic epilepsy (JME) by collecting blood samples from over 1,000 people with JME across the UK, Europe, and North America. Researchers will compare their DNA to samples from 2,000 healthy controls. The goal is to improve treatments and enable earlier detection of the condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could point toward better treatments and earlier detection for juvenile myoclonic epilepsy.
- What could go wrong
- This is an observational study, not a treatment trial. It may not directly lead to new therapies, and genetic findings can take years to translate into clinical use.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Charles University
RECRUITINGPrague, 116 36, Czechia
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Commissione Genetica Lega Italiana contro l'Epilepssia
RECRUITINGRoma, 00198, Italy
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Danish National Epilepsy Centre
RECRUITINGDianalund, 4293, Denmark
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Hospital for Sick Kids
RECRUITINGToronto, Ontario, M5G 0A4, Canada
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King's College Hospital NHS Trust
RECRUITINGLondon, SE5 9RS, United Kingdom
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Mount Sinai-Beth Israel Medical Center
COMPLETEDNew York, New York, 10003, United States
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Nationwide Children's Hospital
COMPLETEDColumbus, Ohio, 43125, United States
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Royal London Hospital
RECRUITINGLondon, E1 1BZ, United Kingdom
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St Luke's Roosevelt Hospital
COMPLETEDNew York, New York, 10025, United States
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St Thomas' Hospital
RECRUITINGLondon, SE1 9HT, United Kingdom
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Swansea University
RECRUITINGSwansea, SA2 8PP, United Kingdom
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Tallinn Children's Hospital
RECRUITINGTallinn, 13419, Estonia
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University Robert Debré
RECRUITINGParis, 75019, France
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Vestre Viken Health Trust, Oslo
RECRUITINGDrammen, 3004, Norway
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Walton Centre for Neurology and Neurosurgery
RECRUITINGLiverpool, L9 7LJ, United Kingdom
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