New filler injection aims to smooth smile lines in chinese adults

NCT ID NCT05454033

First seen Jan 05, 2026 · Last updated May 12, 2026 · Updated 20 times

Summary

This study tested whether JUVÉDERM® VOLITE™, an injectable gel, can safely improve lines around the mouth in Chinese adults. About 198 participants with moderate to severe lines received either the filler or no treatment. The main goal was to see if the filler reduced line severity by at least one grade on a 4-point scale over 12 months.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PERIORAL LINES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Beijing Hospital /ID# 231393

    Beijing, Beijing Municipality, 100730, China

  • China-Japan Friendship Hospital /ID# 252139

    Beijing, Beijing Municipality, 100029, China

  • Hangzhou First People's Hospital /ID# 244111

    Hangzhou, Zhejiang, 310003, China

  • Huashan Hospital, Fudan University /ID# 231395

    Shanghai, Shanghai Municipality, 200040, China

  • Nanjing Drum Tower Hospital /ID# 231937

    Nanjing, Jiangsu, 210008, China

  • Peking University First Hospital /ID# 231392

    Xicheng District, Beijing Municipality, 100034, China

  • Plastic Surgery Hospital(Institute), Cams, Pumc /ID# 231394

    Beijing, Beijing Municipality, 100144, China

  • The Third Affiliated Hospital, Sun Yat-Sen University /ID# 231398

    Guangzhou, Guangdong, 510630, China

  • Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 231396

    Wuhan, Hubei, 430022, China

  • West China Hospital, Sichuan University /ID# 231740

    Chengdu, Sichuan, 610041, China

  • Zhongda Hospital Southeast University /ID# 244045

    Nanjing, Jiangsu, 210009, China

Conditions

Explore the condition pages connected to this study.