New gel injection aims to smooth neck wrinkles

NCT ID NCT05741034

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested JUVÉDERM® VOLITE™, a gel made from hyaluronic acid and lidocaine, to safely and effectively reduce neck lines in Chinese adults. About 159 participants with moderate to severe neck lines were randomly assigned to receive the injection or no treatment. The main goals were to see if the gel improved neck lines by at least one grade and to monitor any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

JUVÉDERM® VOLITE™ (hyaluronic acid gel with lidocaine)

What this could lead to

If it works, this could offer a minimally invasive option to reduce neck lines and improve skin quality.

What could go wrong

This is a completed phase 3 trial, but results are not yet published. The treatment is cosmetic, not life-changing, and may cause side effects like swelling or bruising.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Hospital /ID# 243982

    Beijing, Beijing Municipality, 100730, China

  • China-Japan Friendship Hospital /ID# 243984

    Beijing, Beijing Municipality, 100029, China

  • Huashan Hospital, Fudan University /ID# 244044

    Shanghai, Shanghai Municipality, 200040, China

  • Peking University First Hospital /ID# 243980

    Xicheng District, Beijing Municipality, 100034, China

  • The Third Affiliated Hospital, Sun Yat-Sen University /ID# 243987

    Guangzhou, Guangdong, 510630, China

  • Tianjin Medical University General Hospital /ID# 244107

    Tianjin, Tianjin Municipality, 300052, China

  • Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 243981

    Wuhan, Hubei, 430022, China

  • Wuxi People's Hospital /ID# 245875

    Wuxi, Jiangsu, 214023, China

  • Zhongda Hospital Southeast University /ID# 243986

    Nanjing, Jiangsu, 210009, China