New gel injection aims to smooth neck wrinkles
NCT ID NCT05741034
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested JUVÉDERM® VOLITE™, a gel made from hyaluronic acid and lidocaine, to safely and effectively reduce neck lines in Chinese adults. About 159 participants with moderate to severe neck lines were randomly assigned to receive the injection or no treatment. The main goals were to see if the gel improved neck lines by at least one grade and to monitor any side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- JUVÉDERM® VOLITE™ (hyaluronic acid gel with lidocaine)
- What this could lead to
- If it works, this could offer a minimally invasive option to reduce neck lines and improve skin quality.
- What could go wrong
- This is a completed phase 3 trial, but results are not yet published. The treatment is cosmetic, not life-changing, and may cause side effects like swelling or bruising.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Beijing Hospital /ID# 243982
Beijing, Beijing Municipality, 100730, China
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China-Japan Friendship Hospital /ID# 243984
Beijing, Beijing Municipality, 100029, China
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Huashan Hospital, Fudan University /ID# 244044
Shanghai, Shanghai Municipality, 200040, China
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Peking University First Hospital /ID# 243980
Xicheng District, Beijing Municipality, 100034, China
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The Third Affiliated Hospital, Sun Yat-Sen University /ID# 243987
Guangzhou, Guangdong, 510630, China
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Tianjin Medical University General Hospital /ID# 244107
Tianjin, Tianjin Municipality, 300052, China
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Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 243981
Wuhan, Hubei, 430022, China
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Wuxi People's Hospital /ID# 245875
Wuxi, Jiangsu, 214023, China
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Zhongda Hospital Southeast University /ID# 243986
Nanjing, Jiangsu, 210009, China