Can a new pill drain stubborn kidney swelling?

NCT ID NCT06670534

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This trial tests an experimental drug called JMKX003142 in people with kidney-related swelling (edema) that doesn't improve with standard diuretics. Participants take the drug or a placebo once daily for seven days. The study measures changes in body weight, urine output, and leg swelling to see if the drug helps remove excess fluid.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
JMKX003142 tablets
What this could lead to
If effective, this could offer a new treatment option for kidney-related swelling that doesn't respond to standard diuretics.
What could go wrong
This is an early-phase trial, so the drug may not prove effective or safe. It's also a short-term study, so long-term benefits and risks are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fudan University Affiliated Zhongshan Hospital

    Shanghai, 200102, China

  • Zhejiang Hangyu Pharmaceutical Co., Ltd(subsidiary of Jemincare)

    Shanghai, 200102, China

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